A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Singh, Amita
- Frequency, Preferences and Prescribing Pattern of Antihypertensive Drugs in Out-Patient Department of a Tertiary Care SGM Hospital, Rewa District of Madhya Pradesh, India
Authors
1 Department of Pharmacology, S.S. Medical College, Rewa, MP, IN
2 Department of Medicine, S.S. Medical College, Rewa, MP, IN
3 Integral Institute of Medical Science & Research, Lucknow, UP, IN
4 Department of Pharmacology, S.S. Medical College, Rewa, MP, IN
5 Department of Physiology, S.S. Medical College, Rewa, MP, IN
Source
The Indian Practitioner, Vol 69, No 3 (2016), Pagination: 32-39Abstract
Aims and Objectives: The aim of study was to determine the frequency and prescribing pattern of antihypertensive drugs in Out Patient Department of a tertiary care hospital and to identify whether the pattern of prescribing is appropriate in accordance with national and international guidelines for pharmacotherapy of hypertension.Methods: This was a prescription-based survey; the prescriptions were collected randomly from OPDs of SGM Hospital as xerox copies after taking the consent of the patients. A total of 3587 prescriptions were analysed.
Results: In the 3587 prescriptions a total 8144 drugs were prescribed; of these only 4.19% (342) drugs belonged to the cardiovascular group. Among the cardiovascular drugs 94.73% (324) belonged to antihypertensive and 5.26% were anti-CHF drugs. 91.35% drugs were prescribed as monotherapy and 8.64% as combination therapy. The Calcium channel blockers (CCBs) (Amlodipine 83.47%) were the most frequently prescribed antihypertensive drugs (35.49%) followed by Angiotensin-converting-enzyme inhibitors (ACEIs) 25% (Enalapril 60.49%), β-blockers 13.27% (Atenolol 69.76%), angiotensin (AT1) receptor antagonists or angiotensin receptor blockers (ARBs) 9.25% (Losartan 80.0%), combination therapy 8.64% (AT+AM/LO+HCTZ 46.42%) and diuretics 8.33% (Hydrochlorothiazide 55.55%). However over all prescribing frequency among antihypertensive drugs were as follows: Amlodipine (29.63%) ≥ Enalapril (15.12%) ≥ Ramipril (9.87%) ≥ Atenolol ≥ (9.25%) ≥ Losartan (7.40%) hydrochlorothiazide ≥ (4.63%) ≥ Es-amlodipine (4.32%) ≥ AT+AM (4.01%)= LO+HCTZ (4.01%) ≥ Frusemide (3.70%) ≥ Candesartan (1.85%) ≥ Metoprolol (1.54%) and others.
Conclusions: Most of antihypertensive drugs in this study were prescribed as monotherapy. Amlodipine was most frequently prescribed antihypertensive followed by Enalapril ≥ Ramipril ≥ Atenolol ≥ and Losartan, in combination therapy AT+AM and LO+HCTZ were equally prescribed. The pattern of this study was in accordance with the National and International guidelines.
Keywords
Hypertension, Angiotensin Converting Enzyme Inhibitors, Calcium Channel Blockers, Angiotensin Receptor Blockers.
- Menstrual Pattern and Prevalence of Menstrual Disorders among Women and Adolescent Girls Residing in the Rural Area of Central India, Rewa, Madhya Pradesh
Authors
1 Physiology, SS. Medical College, IN
2 PHC Devtalab, Rewa, MP, IN
3 Pharmacology, SS. Medical College, Rewa, MP-486001, IN
Source
The Indian Practitioner, Vol 71, No 12 (2018), Pagination: 18-22Abstract
Menstruation is a natural, normal biological process experienced by all adolescent girls and women in reproductive age.
Aim & Objectives: The aim of study is to determine the patterns of menstruation and identify the prevalence of common menstrual disorders among women of reproductive age groups residing in the rural areas.
Material and Methods: In this cross-sectional study, total 171 participants were enrolled; the desired information was collected by personal interview with a self designed questionnaire that contained information regarding demographic parameters and menstrual cycle characteristics and prevalence of menstrual problems. Statistical data analysis was performed with Microsoft Office Excel 2007 and expressed in numbers and percentages.
Results: The age of menarche in majority of participants 79 (46.19%) was between 12-13 years; menstrual cycles were regular in 129 (75.43%) and irregular in 42 (24.56%) subjects. 117 (68.42%) females reported 3-5 days blood flow during menstruation, 24 (14.03%) less than 3 days and 30 (17.54%) had more than 5 days of menstruation. 12 (7.01%) girls reported scanty blood loss, 135 (78.94%) medium blood flow and 24 (14.03%) heavy blood flow, cycle length was shorter than 21 days in 36 (21.05%), between 21-35 days in 123 (71.93%) and longer than 35 days in 12 (7.01%). The overall prevalence of dysmenorrhoea was 102 (59.64%). Dysmenorrhoea affected daily activities in 90 (52.63%) participants. Premenstrual symptoms were present in 113 (66.08%) girls.
Conclusion: The result of study concluded that significant number of participants had irregular menstrual cycles, abnormal duration of blood flow and abnormal amount of blood loss during menstruation. PMS and dysmenorrhoea were the most common menstrual disorders.
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- Pattern and Frequency of Spontaneously Reported Suspected ADRs in Admitted Patients at a Tertiary Care Hospital of Central India: A Pharmacovigilance Study
Authors
1 Associate Professor, Department of Pharmacology, S.S. Medical College, Rewa, Madhya Pradesh, IN
2 Assistant Professor, Department of Physiology, S.S. Medical College, Rewa, Madhya Pradesh, IN
3 AYUSH Medical Officer, Department of Ayush, Medical Officer, PHC, Devtalab, Rewa, Madhya Pradesh, IN
4 Department of Pharmacology, S.S. Medical College, Rewa, Madhya Pradesh, IN
5 Professor & Head, Department of Pharmacology, S.S. Medical College, Rewa, Madhya Pradesh, IN
6 3rd year PG Resident, Department of Pharmacology, S.S. Medical College, Rewa, Madhya Pradesh, IN
Source
The Indian Practitioner, Vol 74, No 11 (2021), Pagination: 23-29Abstract
Background: ADRs constitute an enormous burden for society and it is one of the leading causes of death. ADRs are poorly and inadequately reported and up to 57% of ADRs are unrecognized by attending physicians.
Aims & Objectives: The aim of this study is to assess the frequency, clinical pattern and spectrum of suspected ADRs in admitted patients.
Material & Methods: This study was conducted, in a multidisciplinary tertiary care hospital, in which a total of 54 cases with suspected ADRs were enrolled. Data was collected by a researcher through telephonic conversation by healthcare professionals from the admitted patients of hospital in CDSCO - ADR reporting form. The data were analyzed by Microsoft word - excel version 2007. All the multiple responses were presented in terms of numbers and percentage.
Results: In the present study, maximum patients (31.48%) belonged to 26-40 years age group, of these maximum patients (35.18%) belonged to lower middle socioeconomic status. Majority of patients (68.51%) were residents of rural areas. Skin & mucous membranes and gastrointestinal system were most frequently (37.18%) involved organ systems; most frequent ADR (17.58%) was skin rashes, followed by pruritus (13.56%). Majority (56.78%) of suspected ADRs were associated with antimicrobials. Among antimicrobials, ceftriaxone + sulbactam is associated with majority (34.51%) of suspected ADRs.
Conclusion: ADR monitoring is the key component of effective drug regulation systems, clinical practice and public health programmes. Hospital based ADR monitoring and reporting programmes aim to identify and quantify the risks associated with the use of the drugs.
Keywords
Pharmacovigilance Program of India, PvPI, Adverse Drug Event, Adverse Drug Reaction, Central Drugs Standard Control Organization, CDSCO.References
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